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Can people be allergic to exercise?

Some people break out in hives.

Imagine a woman has a few drinks one night, pops some ibuprofen in the morning for her hangover, and goes for a run. She’s never had an issue with alcohol, ibuprofen or exercise before. But this time, some combination of the three triggers a life-threatening allergic reaction known as anaphylaxis.

This is a real case that happened to a patient of Dr. Andrew Murphy, an allergist at Suburban Allergy Consultants in Pennsylvania. So, is it possible to be allergic to exercise?

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